Ambulatory Oxygen Therapy for Individuals With Mild-to-moderate Interstitial Lung Disease

Status: Recruiting
Location: See location...
Intervention Type: Drug, Behavioral
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

The investigators plan to conduct a study to find out if giving portable oxygen therapy (during physical activity) to patients with interstitial lung disease will improve quality of life, exercise tolerance, shortness of breath, and blood vessel function. Oxygen will be provided for a period of 8 weeks. Additionally, the investigators plan to investigate if it is helpful to deliver individualized support when providing oxygen therapy, through check-in phone calls with a respiratory therapist and by providing additional educational material.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Individuals with fibrotic ILD (all sub-groups of ILD) who have normal oxygen saturation at rest (SpO2 \> 90%) but develop exertional hypoxemia as demonstrated by a SpO2 = 80-89% with activity (measured during 6MWT).

Locations
Other Locations
Canada
Clinical Physiology Laboratory
RECRUITING
Edmonton
Contact Information
Primary
Matt Rieger, PhD
mrieger@ualberta.ca
7804928027
Backup
Desi Fuhr, MSc
fuhr@ualberta.ca
780.492.1121
Time Frame
Start Date: 2025-07-01
Estimated Completion Date: 2026-09-01
Participants
Target number of participants: 60
Treatments
No_intervention: Arm 1 - Usual Care
8 weeks of usual care with no supplemental oxygen provided
Experimental: Arm 2 - Exertional Oxygen
8 weeks of portable oxygen use (from a concentrator) during exertion
Experimental: Arm 3 - Exertional Oxygen + Support
8 weeks of portable oxygen use (from a concentrator) during exertion, plus additional phone calls with a respiratory educator and educational material
Sponsors
Collaborators: Alberta Boehringer Ingelheim Collaboration
Leads: University of Alberta

This content was sourced from clinicaltrials.gov